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COMBIA: Synergy/Antagonism Analyses of Drug Combinations

A comprehensive synergy/antagonism analyses of drug combinations with quality graphics and data. The analyses can be performed by Bliss independence and Loewe additivity models. COMBIA provides improved statistical analysis and makes only very weak assumption of data variability while calculating bootstrap intervals (BIs). Finally, package saves analyzed data, 2D and 3D plots ready to use in research publications. COMBIA does not require manual data entry. Data can be directly input from wetlab experimental platforms for example fluostar, automated robots etc. One needs to call a single function only to perform all analysis (examples are provided with sample data).

COMBIA.pdf