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CopulaDTA: Copula Based Bivariate Beta-Binomial Model for Diagnostic Test Accuracy Studies

Modelling of sensitivity and specificity on their natural scale using copula based bivariate beta-binomial distribution to yield marginal mean sensitivity and specificity. The intrinsic negative correlation between sensitivity and specificity is modelled using a copula function. A forest plot can be obtained for categorical covariates or for the model with intercept only.

CopulaDTA.pdf