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epoc: EPoC (Endogenous Perturbation analysis of Cancer)

Estimates sparse matrices A or G using fast lasso regression from mRNA transcript levels Y and CNA profiles U. Two models are provided, EPoC A where AY + U + R = 0 and EPoC G where Y = GU + E, the matrices R and E are so far treated as noise. For details see the reference and the manual page of ‘lassoshooting’.

epoc.pdf