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fcros: A Method to Search for Differentially Expressed Genes and to Detect Recurrent Chromosomal Copy Number Aberrations

A fold change rank based method is presented to search for differentially expressed genes and to detect recurrent chromosomal copy number aberrations. This method may be useful for high-throughput biological data (microarray, sequencing, ...). Probabilities are associated with genes/probes in the dataset and there is no problem of multiple tests when using this method. For aCGH data, segmentation results are obtained by merging the significant probes detected.

fcros.pdf